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CS is associated with greater levels of inflammatory markers such as interleukin (IL)-6, C-reactive protein (CRP), and tumor necrosis factor (TNF)-in smokers in both sexes (32, 33)

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Some of the identified TSNAs, aldehydes, metals, VOCs, phenolic compounds, PAHs, and tobacco alkaloids are harmful or potentially harmful constituents, and their general health risks are described below

Sport, however, especially football, cricket and golf, remained very popular, reflecting the early dominance of men as smokers