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Additionally, in human gastric adenocarcinoma, 8-paradol exacerbates PINK1-Parkin-mediated mitophagy to decrease the expression of BCL2, whereas it increases the expression levels of BAX, cytochrome c, and caspase-9/3, ultimately inducing intrinsic apoptosis [26]

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In Sub-Saharan Africa, tobacco use among youth is rising due to targeted industry marketing and weak regulatory enforcement

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