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While comprehensive in scope, the studys small sample size, lack of microbiome data, and absence of mechanistic experimentation limit the ability to draw causal conclusions
Rodrigues, Jean-Marie, David Robinson, Vincenzo Della Mea, James Campbell, Alan Rector, Stefan Schulz, Hazel Brear et al
That study raised the possibility that oral beta-carotene supplements might actually have harmful effects in smokers and might increase lung cancer rates.46 A newer study117 also has documented the possible adverse effects of oral beta-carotene on lung cancer
Table 1 Nicotine contents in pouches of 2024 US market-leading brands (top) compared to newly identified 6MN pouch brands (bottom), with 6MN trademarks, flavors and declared 6MN contents The listed 6-methyl nicotine contents of the newly introduced products are either identical to (8 mg) or by far exceed (15 mg, 25 mg), the maximal nicotine contents of the most popular US-marketed nicotine pouch products (Zyn, Velo, On!), marketed in strengths of 1.58 mg (Table 1) 11-14
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