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Ethical approval The study protocol was approved by the University of California, San Diego Human Research Protections Program

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Discussion Using Australia as an example of a high-income country with successfully implemented tobacco control initiatives, resulting in declining cigarette smoking and tobacco consumption, we have projected the future national burden of cancer deaths from smoking-related cancers

Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study