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Chronic constipation affects 27% of the population in Western countries, with a higher prevalence among women, older individuals, and those with lower socio-economic status (1)

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Multilevel modelling was performed using the STATA 15 and MLwiN 3.09 software program (using runmlwin ) and the Markov Chain Monte Carlo (MCMC) method using the Gibbs sampler, keeping the default prior distribution of Iterated Generalized Least Squares (IGLS) as the starting value [22,23,24]

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