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This approach allowed us to systematically identify all relevant studies indexed in PubMed up to 31 May 2022, and we extracted relevant data on risk of smoking, including study characteristics, following a pre-specified template (Supplementary Table 2)

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What most people remember about Gehrig, thanks to Gary Coopers portrayal in The Pride of the Yankees, is his simple, decent, sweet, uncomplaining, stoic response to this awful disease, which ravaged a once virile man until he could not walk or speak or swallow