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Food and Drug Administration is "pushing very hard" to release a proposed rule that would establish its authority over e-cigarettes, the head of the agency said on Thursday amid concerns the products pose a risk to children

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Limited animal studies using histologic examinations of renal tissue or measurements of renal function indicate that e-cig use can increase susceptibility to CKD and progression of CKD in experimental models [55,56,57,58,59,60,61]

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