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Patients exceeding the 5.6% 10-year risk threshold (representing the 80th percentile of estimated risk in the epidemiological cohorts) were classified as high-risk for surveillance

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shortly thereafter they were offered in the New York metropolitan market and gradually the distribution was extended to the other parts of the country

The first and most obvious assumption was that these nicotine levels were still due to nicotine-containing insecticides (Sheen 1988) illegally used after banning