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Although the main risk factor for AD is aging, various others factors have also been proposed, including gender, ApoE polymorphism, the coexistence of other disorders (such as cardiovascular diseases, brain injury, diabetes and Down syndrome) and several lifestyle conditions, including physical activity, education, diet or smoking 4,5

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The FDA declined to weigh in specifically on the Black & Mild name but is reviewing more than 75,000 comments on its proposals.