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70 The RESTORE study, a prospective randomized, double-blind, placebo-controlled study of patients with GOLD stage II and III COPD, showed that patients who received erdosteine 300 mg twice daily added to usual treatment reduced exacerbation rates by 19.4% (0.91 versus 1.13 exacerbations/patient/year, p =0.01), mostly due to a reduction of mild exacerbations

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As time goes on, however, it becomes more apparent that they cannot quit and they turn to the second maladaptive response: resignation

Interestingly, while vaping and smoking are strictly prohibited on the plane, laws in the US, EU, UK, and Canada actually require passengers to pack these items with them in their carry-on bag as theyre not allowed to be in hold luggage

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