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More pack-years are associated with a higher risk of lung disease.

Since 2016, the Duterte administration has been aggressive in implementing regulatory measures that discourage nicotine addiction, such as the ban on smoking in public and the high excise tax on tobacco

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These findings emphasize the need for high-quality studies using objective diagnostic measures to better assess the link between e-cigarette use and the odds of having COPD

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Notably, carbonyl compounds such as formaldehyde, acetaldehyde, and acrolein are released when PG/VG solvents are heated, and these reactive aldehydes are well-recognized respiratory irritants and potential carcinogens (34)