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Moreover, smokers have increased expression of CYP1A1, which can increase the metabolism ARTs that undergo metabolism through this pathway, such as dolutegravir resulting in a higher drug clearance value (Zhu et al., 2018)

Strumylaite L, Kregzdyte R, Vaitkaitiene E (2005) Pasyvus rukymas ir vaiku kvepavimo sutrikimai [Passive smoking and respiratory health of children]

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Indeed, in parts of Europe, it seemed like half the population smoked

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