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Even more amazingly, VLN, by then a registered trademark, became the first combustible cigarette product in the US to ever having successfully gone through both the pre-market tobacco product application [PMTA] and the modified risk tobacco product [MRTP] processes

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For the 14 days of the trial, participants were trained to record every cigarette they smoked using project-provided smartphones and to complete a daily evening report (see Thrasher et al

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