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Another case study reported the same observation for a 16-year-old youth who started using IQOS 2 weeks before hospitalization 111

Each cone is carefully packaged in a premium triple-layer carton box, designed for maximum durability and a refined look

Harrison et al

This was designed to equalize pressure and reduce condensation by allowing air to flow freely into and out of the sealed enclosure

Among 746,485 smokers enrolled in the American Cancer Prevention Study II, the association between duration and lung cancer mortality (risk ratio for log-transformed years ranging from 3.5 to 16) was exponentially greater than for cigarettes per day (risk ratio for log transformed intensity ranging from 1.4 to 2.6) across strata of age and sex (9)

And such agencies as the FDA have recognized IQOS as a Modified Risk Tobacco Product, enabling marketing that can depict it as being potentially less harmful than the usual smoking