Discussion Given the critical role of mitochondrial function in the pathophysiology of COPD and its reported association with nDNA methylation, we set out to explore the effect of cigarette smoke exposure on DNA methylation of the mitochondrial genome
Selon un mode particulier de ralisation de l'invention, le procd de prparation du solide selon l'invention, peut comprendre en outre une tape (ii) d'introduction dans les pores ou la surface du solide MOF, d'au moins une molcule d'intrt, qui peut tre un principe pharmaceutiquement actif et/ou un compos d'intrt en cosmtique et/ou marqueur.According to one particular embodiment of the invention, the process for preparing the solid according to the invention may further comprise a step (ii) of introducing into the pores or on the surface of the MOF solid at least one molecule of interest, which may be a pharmaceutically active ingredient and / or a compound of interest in cosmetics and / or marker
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