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A review of multiple studies found that six studies reported a decrease in adolescent use, while seven studies reported an increase in use

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Twenty-three studies 18,22,25-29,31,33,35-37,39,40,42-48,50,52 (59%) evaluated the effects of acute exposure, nine studies 15,17,26,29,33,34,41,49,51 (23%) short-to-medium term exposure, and one study 20 (3%) examined effects of long-term exposure