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6 Boot and shoe manufacture and repair: Linked to increased risk of nasal cancer and leukaemia, due to exposure to suspected carcinogens such as leather dust, benzene and other solvents, yet the risk of cancer in shoe manufacturing may vary depending on the duration and level of exposure

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Treatment with higher CSC concentrations (100 g/ml) had no effect on P53 protein expression, although the knock down of P53 shows a minimal protective effect (increase in viability compared with control cells of 8%)