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This does not mean quitting is impossible, it highlights the importance of structured support and preparation

Furthermore, even when dysplasia is present in ST leukoplakia, it usually is found in earlier stages than in leukoplakias due to smoking [62, 63], where it is seen in about 20% of cases [64]

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Factors affecting nicotine and elimination and detection time include metabolic rate, frequency of use, urinary pH, and individual factors

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