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This 10-item scale (with scores ranging from 0 to 20) was developed to measure nicotine dependence across all nicotine product types, and an adapted version was the first dependence measure designed to evaluate electronic cigarette dependence

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It is characterized by pigmented macrophage accumulation within bronchioles (Fig

The NHS does not list nicotine pouches as a recognised form of nicotine replacement therapy, however, many of the nicotine products they do recommend such as gum, lozenges and oral strips contain many of the same ingredients as nicotine pouches