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Methods Cigarette consumption data This study draws on a previous systematic collection and quality appraisal of national cigarette consumption data from 1970 to 2015.19 Although survey-based data offer advantages of capturing cigarette use prevalence and smoking intensity, variations in survey questions and sporadic nationally representative data coverage do not allow for the systematic comparison of cigarette consumption across countries and over time.22 By contrast, country-level cigarette consumption obscures the division between cigarette use prevalence and smoking intensity but is reported annually in comparable units by nearly all European countries.23 24 In brief, the source data were compiled using an adaptive search strategy to collect data from all national statistical agencies on production, trade and sales of cigarettes with supplemental data from international sources, academic and grey literature, and subject matter experts.19 Data were appraised by two researchers to evaluate intersource consistency and data confidence, resulting in an open-access dataset of cigarette consumption estimates for 71 countries representing over 95% of the worlds cigarette consumption and 85% of the worlds population.20 A single year was chosen as a break point at which to divide countries of the former USSR (1995), Yugoslavia (1990) and Czechoslovakia (1992), and at which to unite East Germany and West Germany (1990)
Biomark Med 11:475489 Nunnari J, Suomalainen A (2012) Mitochondria: in sickness and in health
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