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2000b Tobacco Control: Country Profiles American Cancer Society: Atlanta, GA Cosma G, Crofts F, Currie D, Wirgin I, Toniolo P, Garte S

These observations indicate a deterministic shift of healthy oral microbiome during environmental stress conditions, like tobacco consumption, to a more dispersed microbial community composition in tobacco consuming individuals that is similar to the microbiome associated with OSCC buccal site ( Figure 7 )

[9] It reached number nine on the US Billboard Top LPs & Tape chart and remained on the chart for 51 weeks

27,28 The histologic subtypes of lung cancer seen in the US population have also shifted with time