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This MR study included two smoking-related traits: age of smoking initiation ( n = 341,427) and cigarettes per day ( n = 337,334)

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This wasn't the first study to note the corporate coverup;an earlier report in American Journal of Public Health reached the same conclusion

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We estimate that smoking causes at least half of the remaining 17 percent through diseases that have not previously been recognized as being caused by cigarette smoking, said Neal Freedman, Ph.D., a co-investigator on the study from NCIs Division of Cancer Epidemiology and Genetics