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Number of puffs taken and puff duration tend to decrease as nicotine strength of the e-liquid increases

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A small clinical study investigating the pulmonary effects of vaping e-cigs containing only PG/VG found no significant difference in inflammatory cell count and cytokine expression in BALF after four weeks between e-cig users and a non-user control group 41

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One consistent finding is that smokers with ADHD have more severe smoking withdrawal, including craving and negative mood