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Some brands have even higher nicotine concentrations

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Endgame Strategies The Tobacco Endgame is a set of initiatives that seeks to eradicate tobacco use by establishing strategies that eliminate the social, political, and structural constructs that allow the tobacco epidemic to continue. [ 18 ] In 2023, we saw an increasing number of middlegame policies that limit the number of tobacco retailers permitted in a jurisdiction, and some additional policies that sunset licenses for retailers, phasing them out over time

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Furthermore, they seem to have the potential to be more predictive of effects in humans since they are derived from biopsied human cells and contain many of the relevant differentiated cell types not found in monolayer cultures