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Dose adaption or even a change of medication might be indicated in smokers with BD, i.e., for olanzapine and clozapine a 50% higher dosage might be required (65)

But there's more to the story, especially when it comes to cotinine testing and workplace tobacco policies

They use drums that are entirely painted white, and they seem to paint themselves

or increased or decreased interest in sex

62 So, even with a larger puff, the same mass of toxins can seem less harsh and irritating because it is diluted by a proportionate amount of air, which may in turn underscore smokers beliefs that they are smoking safer cigarettes