Figure 1 Dopaminergic Dysfunction The dopamine (DA) hypothesis for SZ features the imbalances in dopaminergic neurotransmission throughout the brain, such as presynaptic abnormalities of DA neurons that are described in both SZ and high-risk populations (60, 61)
Managing Stress and Other Risk Factors Chronic stress doesnt just affect your mood
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Risk depends on the specific concern acute physical danger, addiction potential, and long-term health impact don't always point the same direction, which is why a substance-specific evaluation matters more than a general ranking