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10.1016/j.ejphar.2007.05.072 69 TodaN.NakanishitodaM

Nevertheless, I think your recommendations make sense

And so, a lot of these people who are waking up in the middle of the night to pee I think have depressed levels of vasopressin and it could be that their circadian rhythm is just messed up, right

p53-pS15 is a major focal point in p53 activation to mediate p53-dependent transcription or growth arrest, Ser 15 phosphorylation triggers a sequence of additional sites phosphorylation in p53 (including Ser9, -20, -46 and Thr18) that contribute further to p53 activation 28

PMID 33053716

In addition, the suppression of EPO on hepcidin expression may be related to the erythroferrone (ERFE) produced by erythroblasts in response to EPO, which could target hepatic BMP/SMAD signaling via preferentially impairing an evolutionarily closely related BMP subgroup of BMP5, BMP6, and BMP7 [5456]